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1

A physiome interoperability roadmap for personalized drug development

Thomas, Simon, Wolstencroft, Katherine, de Bono, Bernard, Hunter, Peter J.

Journal:

Interface Focus

Year:

2016

Language:

english

File:

PDF, 1.09 MB

english, 2016

2

The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable

Nickerson, David, Atalag, Koray, de Bono, Bernard, Geiger, Jörg, Goble, Carole, Hollmann, Susanne, Lonien, Joachim, Müller, Wolfgang, Regierer, Babette, Stanford, Natalie J., Golebiewski, Martin, Hunt

Journal:

Interface Focus

Year:

2016

Language:

english

File:

PDF, 775 KB

english, 2016

3

Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders

Hofmann-Apitius, Martin, Ball, Gordon, Gebel, Stephan, Bagewadi, Shweta, de Bono, Bernard, Schneider, Reinhard, Page, Matt, Kodamullil, Alpha, Younesi, Erfan, Ebeling, Christian, Tegnér, Jesper, Canar

Journal:

International Journal of Molecular Sciences

Year:

2015

Language:

english

File:

PDF, 5.02 MB

english, 2015

4

Model annotation and discovery with the Physiome Model Repository

Sarwar, Dewan M., Kalbasi, Reza, Gennari, John H., Carlson, Brian E., Neal, Maxwell L., Bono, Bernard de, Atalag, Koray, Hunter, Peter J., Nickerson, David P.

Journal:

BMC Bioinformatics

Year:

2019

Language:

english

File:

PDF, 2.10 MB

english, 2019

5

SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans

Huan Cao, Ursula Lakner, Bernard de Bono, James A. Traherne, John Trowsdale, Alexander D. Barrow

Journal:

European Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 761 KB

english, 2008

6

Integrating systems biology models and biomedical ontologies

Robert Hoehndorf, Michel Dumontier, John H Gennari, Sarala Wimalaratne, Bernard de Bono, Daniel L Cook, Georgios V Gkoutos

Journal:

BMC Systems Biology

Year:

2011

Language:

english

File:

PDF, 399 KB

english, 2011

7

Comparative genomics indicates the mammalian CD33rSiglec locus evolved by an ancient large-scale inverse duplication and suggests all Siglecs share a common ancestral region

Huan Cao, Bernard de Bono, Katherine Belov, Emily S. Wong, John Trowsdale, Alexander David Barrow

Journal:

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

8

Relationship between SPRY and B30.2 protein domains. Evolution of a component of immune defence?

David A. Rhodes, Bernard De Bono, John Trowsdale

Journal:

Year:

2005

Language:

english

File:

PDF, 721 KB

english, 2005

9

ApiNATOMY: A novel toolkit for visualizing multiscale anatomy schematics with phenotype-related information

Bernard de Bono, Pierre Grenon, Stephen John Sammut

Journal:

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

10

β-Secretase

Stephanie de Bono, Bernard de Bono

Journal:

Trends in Biochemical Sciences

Year:

2001

Language:

english

File:

PDF, 26 KB

english, 2001

11

With this ring………

Stephanie de Bono, Bernard de Bono

Journal:

Trends in Biochemical Sciences

Year:

2001

Language:

english

File:

PDF, 26 KB

english, 2001

12

Doughnut delivery

Stephanie de Bono, Bernard de Bono

Journal:

Trends in Biochemical Sciences

Year:

2001

Language:

english

File:

PDF, 26 KB

english, 2001

13

Integrating knowledge representation and quantitative modelling in physiology

Bernard de Bono, Prof. Peter Hunter

Journal:

Biotechnology Journal

Year:

2012

Language:

english

File:

PDF, 1.26 MB

english, 2012

14

VH Gene Segments in the Mouse and Human Genomes

Bernard de Bono, Martin Madera, Cyrus Chothia

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 5.99 MB

english, 2004

15

IRIS: A database surveying known human immune system genes

James Kelley, Bernard de Bono, John Trowsdale

Journal:

Year:

2005

Language:

english

File:

PDF, 491 KB

english, 2005

16

Exploring the immunogenome with bioinformatics

Bernard de Bono, John Trowsdale

Journal:

Seminars in Immunology

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

17

The RICORDO approach to semantic interoperability for biomedical data and models: strategy, standards and solutions

Bernard de Bono, Robert Hoehndorf, Sarala Wimalaratne, George Gkoutos, Pierre Grenon

Journal:

BMC Research Notes

Year:

2011

Language:

english

File:

PDF, 1021 KB

english, 2011

18

Eliciting candidate anatomical routes for protein interactions: a scenario from endocrine physiology

Pierre Grenon, Bernard de Bono

Journal:

BMC Bioinformatics

Year:

2013

Language:

english

File:

PDF, 419 KB

english, 2013

19

HuPSON: the human physiology simulation ontology

Gündel, Michaela, Younesi, Erfan, Malhotra, Ashutosh, Wang, Jiali, Li, Hui, Zhang, Bijun, de Bono, Bernard, Mevissen, Heinz-Theodor, Hofmann-Apitius, Martin

Journal:

Journal of Biomedical Semantics

Year:

2013

Language:

english

File:

PDF, 344 KB

english, 2013

20

Functional tissue units and their primary tissue motifs in multi-scale physiology

de Bono, Bernard, Grenon, Pierre, Baldock, Richard, Hunter, Peter

Journal:

Journal of Biomedical Semantics

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

21

RANDOMISED TRIAL OF INTRAVENOUS RECOMBINANT TISSUE-TYPE PLASMINOGEN ACTIVATOR VERSUS INTRAVENOUS STREPTOKINASE IN ACUTE MYOCARDIAL INFARCTION

Verstraete, M., Bory, M., Collen, D., Erbel, R., Lennane, R.J., Mathey, D., Michels, H.R., Schartl, M., Uebis, R., Bernard, R., Brower, R.W., De Bono, D.P., Huhmann, W., Lubsen, J., Meyer, J., Rutsch,

Journal:

Year:

1985

Language:

english

File:

PDF, 760 KB

english, 1985

22

The Open Physiology workflow: modeling processes over physiology circuitboards of interoperable tissue units

de Bono, Bernard, Safaei, Soroush, Grenon, Pierre, Nickerson, David P., Alexander, Samuel, Helvensteijn, Michiel, Kok, Joost N., Kokash, Natallia, Wu, Alan, Yu, Tommy, Hunter, Peter, Baldock, Richard

Journal:

Frontiers in Physiology

Year:

2015

Language:

english

File:

PDF, 6.04 MB

english, 2015

23

[ACM Press the first international workshop - Glasgow, Scotland, UK (2011.10.28-2011.10.28)] Proceedings of the first international workshop on Managing interoperability and complexity in health systems - MIXHS '11 - Integrating volumetric biomedical data in the virtual physiological human

Burger, Albert, de Bono, Bernard, Hunter, Peter, Bisbal, Jesus, Frangi, Alejandro F., Hoogendoorn, Corne, Davidson, Duncan, Gu, Xu, Baldock, Richard

Year:

2011

Language:

english

File:

PDF, 1.44 MB

english, 2011

24

PROSELICA: Health-related quality of life (HRQL) and post-hoc analyses for the phase 3 study assessing cabazitaxel 20 (C20) vs 25 (C25) mg/m2 post-docetaxel (D) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC)

de Bono, J.S., Hardy-Bessard, A-C., Kim, C.S., Géczi, L., Ford, D., Mourey, L., Carles, J., Parente, P., Font, A., Kacsó, G., Chadjaa, M., Zhang, W., Bernard, J., Eisenberger, M.

Journal:

Annals of Oncology

Year:

2016

Language:

english

File:

PDF, 48 KB

english, 2016

25

Automated PDF highlighting to support faster curation of literature for Parkinson’s and Alzheimer’s disease

Wu, Honghan, Oellrich, Anika, Girges, Christine, de Bono, Bernard, Hubbard, Tim J.P., Dobson, Richard J.B.

Journal:

Year:

2017

Language:

english

File:

PDF, 978 KB

english, 2017

26

Reactome: An integrated expert model of human molecular processes and access toolkit

Bono, Bernard de, Vastrik, Imre, D’Eustachio, Peter, Schmidt, Esther, Gopinath, Gopal, Croft, David, Gillespie, Marc, Jassal, Bijay, Lewis, Suzanna, Matthews, Lisa, Wu, Guanming, Birney, Ewan, Stein,

Journal:

Journal of Integrative Bioinformatics

Year:

2007

Language:

english

File:

PDF, 807 KB

english, 2007

27

Reactome - a knowledgebase of human biological pathways

D'Eustachio, Peter, Croft, David, de Bono, Bernard, Gopinath, Gopal, Gillespie, Marc, Jassal, Bijay, Matthews, Lisa, Schmidt, Esther, Vastrik, Imre, Wu, Guanming, Lewis, Suzanna, Birney, Ewan, Stein,

Journal:

Bioentrepreneur

Year:

2007

Language:

english

File:

PDF, 1.73 MB

english, 2007

28

Reactome - a knowledgebase of human biological pathways

Jassal, Bijay, Schmidt, Esther, Wu, Guanming, Vastrik, Imre, Croft, David, de Bono, Bernard, Gopinath, Gopal, Gillespie, Marc, Jupe, Steven, O'Kelly, Gavin, Matthews, Lisa, Garapati, Phani, Caudy, Mic

Journal:

Bioentrepreneur

Year:

2009

Language:

english

File:

PDF, 290 KB

english, 2009

29

Reactome - a knowledgebase of human biological pathways

D'Eustachio, Peter, Croft, David, de Bono, Bernard, Gopinath, Gopal, Gillespie, Marc, Jassal, Bijay, Matthews, Lisa, Schmidt, Esther, Vastrik, Imre, Wu, Guanming, Lewis, Suzanna, Birney, Ewan, Stein,

Journal:

Bioentrepreneur

Year:

2007

File:

PDF, 1.73 MB

2007

30

Reactome - a knowledgebase of human biological pathways

Jassal, Bijay, Schmidt, Esther, Wu, Guanming, Vastrik, Imre, Croft, David, de Bono, Bernard, Gopinath, Gopal, Gillespie, Marc, Jupe, Steven, O'Kelly, Gavin, Matthews, Lisa, Garapati, Phani, Caudy, Mic

Journal:

Bioentrepreneur

Year:

2009

File:

PDF, 290 KB

2009

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